Views: 7 Author: Site Editor Publish Time: 2022-04-13 Origin: Site
Ceramic membrane has the characteristics of low energy consumption, high efficiency, low temperature operation and difficult inactivation of bioactive substances. In recent years, it has been widely used in the separation, concentration and purification of bioactive substances. Application scenarios include: filtration of traditional Chinese medicine extract, filtration of biological fermentation broth, concentration and purification of target products, separation and extraction of enzymes, etc. Let's give you a detailed introduction.
1. The Application of Ceramic Membrane in Filtration of Traditional Chinese Medicine Extract
The components of traditional Chinese medicine extract are very complex, including various effective components, ineffective components and toxic components. Using Inorganic Ceramic Membrane to refine the extract of traditional Chinese medicine and further isolate and purify its effective components can extract its effective components to the limit and give full play to the role of traditional Chinese medicine. Compared with the traditional water extraction and alcohol precipitation process, it has the advantages of no phase change, 100% target interception rate, less water consumption, simple process and convenient operation.
2. The Application of Ceramic Membrane in Biological Fermentation Broth Filtration
Pharmaceutical fermentation broth has its particularity, which is mainly characterized by high mycelial concentration and high viscosity. In addition, most fermentation products are unstable and will be denatured and inactivated under the action of high temperature, acid-base and special solvents, which is easy to cause difficulties in subsequent extraction and purification and affect the quality of products. If ceramic membrane is used, mycelium, metabolites, bacterial fragments and other macromolecular substances in fermentation broth can be effectively removed. It has the advantages of high separation accuracy, high clarity, transparent through liquid and effectively preventing denaturation and inactivation of products. It can obtain clarified or even sterilized filtrate. After continuous top washing, only a very low unit is retained in the residue, which can theoretically obtain a higher extraction rate than plate frame filtration.
3. Ceramic membrane is applied to the concentration and refining of target products
Using ceramic membrane technology to treat the stock solution, low molecular substances such as salt can be removed together with water through the membrane, and the target product can be concentrated and refined. Using ceramic membrane technology instead of vacuum evaporation concentration and other concentration methods can prevent product deactivation, save energy consumption, greatly improve the efficiency of subsequent refining process, shorten process cycle, and improve product quality and yield.
4. The Application of Ceramic Membrane in Enzyme Separation and Extraction
In the traditional separation and extraction methods such as centrifugation, precipitation, dialysis concentration and desalination, the collected enzyme solution needs to be further concentrated due to its low enzyme activity, which has the disadvantages of many processes, high energy consumption, easy inactivation and low recovery rate. Ceramic membrane technology can simplify the process of enzyme extraction, purification and desalination. The utility model has the advantages of simple equipment, convenient operation, high processing efficiency, energy saving, etc. It can separate high concentration bacteria in a very short time without losing enzyme activity.